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Tumor progression is independent of tumor-associated macrophages in cell lineage–based mouse models of glioblastoma
Macrophage targeting therapies have had limited clinical success in glioblastoma (GBM). Further understanding the GBM immune microenvironment is critical for refining immunotherapeutic approaches. Here, we use genetically engineered mouse models and orthotopic transplantation-based GBM models with i...
Autores principales: | Chipman, Mollie E., Wang, Zilai, Sun, Daochun, Pedraza, Alicia M., Bale, Tejus A., Parada, Luis F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120014/ https://www.ncbi.nlm.nih.gov/pubmed/37040416 http://dx.doi.org/10.1073/pnas.2222084120 |
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