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A small-molecule degrader of TET3 as treatment for anorexia nervosa in an animal model

Anorexia nervosa (AN) is a psychiatric illness with the highest mortality. Current treatment options have been limited to psychotherapy and nutritional support, with low efficacy and high relapse rates. Hypothalamic AgRP (agouti-related peptide) neurons that coexpress AGRP and neuropeptide Y (NPY) p...

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Detalles Bibliográficos
Autores principales: Lv, Haining, Catarino, Jonatas, Li, Da, Liu, Beibei, Gao, Xiao-Bing, Horvath, Tamas L., Huang, Yingqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120042/
https://www.ncbi.nlm.nih.gov/pubmed/37036983
http://dx.doi.org/10.1073/pnas.2300015120