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A small-molecule degrader of TET3 as treatment for anorexia nervosa in an animal model
Anorexia nervosa (AN) is a psychiatric illness with the highest mortality. Current treatment options have been limited to psychotherapy and nutritional support, with low efficacy and high relapse rates. Hypothalamic AgRP (agouti-related peptide) neurons that coexpress AGRP and neuropeptide Y (NPY) p...
Autores principales: | Lv, Haining, Catarino, Jonatas, Li, Da, Liu, Beibei, Gao, Xiao-Bing, Horvath, Tamas L., Huang, Yingqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120042/ https://www.ncbi.nlm.nih.gov/pubmed/37036983 http://dx.doi.org/10.1073/pnas.2300015120 |
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