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Optimal generation of hepatic tissue-resident memory CD4 T cells requires IL-1 and IL-2

Hepatic CD4 tissue-resident memory T cells (TRM) are required for robust protection against Salmonella infection; however, the generation of this T cell population is poorly understood. To interrogate the contribution of inflammation, we developed a simple Salmonella-specific T cell transfer system...

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Detalles Bibliográficos
Autores principales: Depew, Claire E., Rixon, Jordan A., McSorley, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120061/
https://www.ncbi.nlm.nih.gov/pubmed/37040404
http://dx.doi.org/10.1073/pnas.2214699120