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Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction

The outer membrane of gram-negative bacteria prevents many antibiotics from reaching intracellular targets. However, some antimicrobials can take advantage of iron import transporters to cross this barrier. We showed previously that the thiopeptide antibiotic thiocillin exploits the nocardamine xeno...

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Detalles Bibliográficos
Autores principales: Chan, Derek C. K., Josts, Inokentijs, Koteva, Kalinka, Wright, Gerard D., Tidow, Henning, Burrows, Lori L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120069/
https://www.ncbi.nlm.nih.gov/pubmed/37043535
http://dx.doi.org/10.1073/pnas.2221253120