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Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction
The outer membrane of gram-negative bacteria prevents many antibiotics from reaching intracellular targets. However, some antimicrobials can take advantage of iron import transporters to cross this barrier. We showed previously that the thiopeptide antibiotic thiocillin exploits the nocardamine xeno...
Autores principales: | Chan, Derek C. K., Josts, Inokentijs, Koteva, Kalinka, Wright, Gerard D., Tidow, Henning, Burrows, Lori L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120069/ https://www.ncbi.nlm.nih.gov/pubmed/37043535 http://dx.doi.org/10.1073/pnas.2221253120 |
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