ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA

BACKGROUND: Liquid biopsies and the dynamic tracking of somatic mutations within circulating tumour DNA (ctDNA) can provide insight into the dynamics of cancer evolution and the intra-tumour heterogeneity that fuels treatment resistance. However, identifying and tracking dynamic changes in somatic c...

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Detalles Bibliográficos
Autores principales: Huebner, Ariana, Black, James R. M., Sarno, Francesca, Pazo, Roberto, Juez, Ignacio, Medina, Laura, Garcia-Carbonero, Rocio, Guillén, Carmen, Feliú, Jaime, Alonso, Carolina, Arenillas, Carlota, Moreno-Cárdenas, Ana Belén, Verdaguer, Helena, Macarulla, Teresa, Hidalgo, Manuel, McGranahan, Nicholas, Toledo, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120117/
https://www.ncbi.nlm.nih.gov/pubmed/37081523
http://dx.doi.org/10.1186/s13073-023-01171-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120117/
https://www.ncbi.nlm.nih.gov/pubmed/37081523
http://dx.doi.org/10.1186/s13073-023-01171-w

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