Cargando…

ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA

BACKGROUND: Liquid biopsies and the dynamic tracking of somatic mutations within circulating tumour DNA (ctDNA) can provide insight into the dynamics of cancer evolution and the intra-tumour heterogeneity that fuels treatment resistance. However, identifying and tracking dynamic changes in somatic c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huebner, Ariana, Black, James R. M., Sarno, Francesca, Pazo, Roberto, Juez, Ignacio, Medina, Laura, Garcia-Carbonero, Rocio, Guillén, Carmen, Feliú, Jaime, Alonso, Carolina, Arenillas, Carlota, Moreno-Cárdenas, Ana Belén, Verdaguer, Helena, Macarulla, Teresa, Hidalgo, Manuel, McGranahan, Nicholas, Toledo, Rodrigo A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120117/ https://www.ncbi.nlm.nih.gov/pubmed/37081523 http://dx.doi.org/10.1186/s13073-023-01171-w

Ejemplares similares

Individualized Mini-Panel Sequencing of ctDNA Allows Tumor Monitoring in Complex Karyotype Sarcomas
por: Braig, David, et al.
Publicado: (2022)

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA
por: Abbosh, Christopher, et al.
Publicado: (2023)

Measurement and analysis of socioeconomic development : an enquiry into international indicators of development and quantitative interrelations of social and economic components of development
por: McGranahan, Donald
Publicado: (1985)

A Neuro-oncologist’s Perspective on Management of Brain Metastases in Patients with EGFR Mutant Non-small Cell Lung Cancer
por: McGranahan, Tresa, et al.
Publicado: (2017)

Urbanization and its implications for food and farming
por: Satterthwaite, David, et al.
Publicado: (2010)

History and current state of immunotherapy in glioma and brain metastasis
por: McGranahan, Tresa, et al.
Publicado: (2017)

Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution
por: Thol, Kerstin, et al.
Publicado: (2022)

Role of ctDNA in Breast Cancer
por: Sant, Marta, et al.
Publicado: (2022)

The Role of ctDNA in Gastric Cancer
por: Mencel, Justin, et al.
Publicado: (2022)

Assessment of a livestock GPS collar based on an open‐source datalogger informs best practices for logging intensity
por: McGranahan, Devan Allen, et al.
Publicado: (2018)

Analysis of intratumor heterogeneity unravels lung cancer evolution
por: de Bruin, Elza C, et al.
Publicado: (2015)

Germline ancestry influences the evolutionary disease course in lung adenocarcinomas
por: Schenk, Alina, et al.
Publicado: (2020)

Liquid Biopsy-Analysis of Circulating Tumor DNA (ctDNA) in Bladder Cancer
por: Todenhöfer, Tilman, et al.
Publicado: (2018)

Utility of ctDNA Liquid Biopsies from Cancer Patients: An Institutional Study of 285 ctDNA Samples
por: Gumà, Josep, et al.
Publicado: (2022)

Current State of Immunotherapy for Treatment of Glioblastoma
por: McGranahan, Tresa, et al.
Publicado: (2019)

deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution
por: Rosenthal, Rachel, et al.
Publicado: (2016)

Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine
por: Hiley, Crispin, et al.
Publicado: (2014)

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution
por: Abbosh, Christopher, et al.
Publicado: (2017)

Chromosomal Microarray Analysis versus Karyotyping in Fetuses with Increased Nuchal Translucency
por: Cicatiello, Rita, et al.
Publicado: (2019)

Habitat associations of bats in a working rangeland landscape
por: Trubitt, Rebecca T., et al.
Publicado: (2018)

Computational optimisation of targeted DNA sequencing for cancer detection
por: Martinez, Pierre, et al.
Publicado: (2013)

Liquid Biopsy, ctDNA Diagnosis through NGS
por: Lin, Chen, et al.
Publicado: (2021)

ctDNA as a biomarker of progression in oesophageal adenocarcinoma
por: Bonazzi, V.F., et al.
Publicado: (2022)

State of the Art: ctDNA in Upper Gastrointestinal Malignancies
por: Labiano, Ibone, et al.
Publicado: (2023)

58. CLINICAL PRESENTATION AND IMAGING CHARACTERISTICS OF LEPTOMENINGEAL CARCINOMATOSIS (LC) IN PATIENTS WITH EGFR MUTATED NON-SMALL CELL LUNG CANCER (NSCLC)
por: Eastman, Boryana, et al.
Publicado: (2020)

Indicators Associated With Job Morale Among Physicians and Dentists in Low-Income and Middle-Income Countries: A Systematic Review and Meta-analysis
por: Sabitova, Alina, et al.
Publicado: (2020)

The circulating tumor DNA (ctDNA) alteration level predicts therapeutic response in metastatic breast cancer: Novel prognostic indexes based on ctDNA
por: Liu, Binliang, et al.
Publicado: (2022)

Potential value of ctDNA monitoring in metastatic HR + /HER2 − breast cancer: longitudinal ctDNA analysis in the phase Ib MONALEESASIA trial
por: Chiu, Joanne, et al.
Publicado: (2023)

Clonal Selection of a Novel Deleterious TP53 Somatic Mutation Discovered in ctDNA of a KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumor Resistant to Imatinib
por: Dalle Fratte, Chiara, et al.
Publicado: (2020)

SEOM clinical guidelines for pancreatic and biliary tract cancer (2020)
por: Gómez-España, Mª A., et al.
Publicado: (2021)

Detection of ctDNA in the plasma of patients with papillary thyroid carcinoma
por: Li, Huiqiang, et al.
Publicado: (2019)

ctDNA: An emerging neoadjuvant biomarker in resectable solid tumors
por: Abbosh, Christopher, et al.
Publicado: (2021)

Current status of ctDNA in precision oncology for hepatocellular carcinoma
por: Li, Yan, et al.
Publicado: (2021)

The potential, analysis and prospect of ctDNA sequencing in hepatocellular carcinoma
por: Ding, Yubo, et al.
Publicado: (2022)

Current and Future Clinical Applications of ctDNA in Immuno-Oncology
por: Stadler, Julia-Christina, et al.
Publicado: (2022)

Regulatory implications of ctDNA in immuno-oncology for solid tumors
por: Vellanki, Paz J, et al.
Publicado: (2023)

CTC, ctDNA, and Exosome in Thyroid Cancers: A Review
por: Wang, Wenwen, et al.
Publicado: (2023)

Living with Psychosis without Mental Health Services: A Narrative Interview Study
por: McGranahan, Rose, et al.
Publicado: (2021)

Management of Brain Metastases from Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Breast Cancer
por: McGranahan, Tresa M., et al.
Publicado: (2022)

Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer
por: Ahrenfeldt, Johanne, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_v5o5693ovnvdm7909un0j5km6k