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PP1γ regulates neuronal insulin signaling and aggravates insulin resistance leading to AD-like phenotypes
BACKGROUND: PP1γ is one of the isoforms of catalytic subunit of a Ser/Thr phosphatase PP1. The role of PP1γ in cellular regulation is largely unknown. The present study investigated the role of PP1γ in regulating neuronal insulin signaling and insulin resistance in neuronal cells. PP1 was inhibited...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120118/ https://www.ncbi.nlm.nih.gov/pubmed/37085815 http://dx.doi.org/10.1186/s12964-023-01071-x |