Gasdermin E regulates the stability and activation of EGFR in human non-small cell lung cancer cells

BACKGROUND: Lung cancer is the most lethal malignancy, with non-small cell lung cancer (NSCLC) being the most common type (~ 85%). Abnormal activation of epidermal growth factor receptor (EGFR) promotes the development of NSCLC. Chemoresistance to tyrosine kinase inhibitors, which is elicited by EGF...

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Detalles Bibliográficos
Autores principales: Xu, Limei, Shi, Feifei, Wu, Yingdi, Yao, Shun, Wang, Yingying, Jiang, Xukai, Su, Ling, Liu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120120/
https://www.ncbi.nlm.nih.gov/pubmed/37085908
http://dx.doi.org/10.1186/s12964-023-01083-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120120/
https://www.ncbi.nlm.nih.gov/pubmed/37085908
http://dx.doi.org/10.1186/s12964-023-01083-7

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