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Gasdermin E regulates the stability and activation of EGFR in human non-small cell lung cancer cells
BACKGROUND: Lung cancer is the most lethal malignancy, with non-small cell lung cancer (NSCLC) being the most common type (~ 85%). Abnormal activation of epidermal growth factor receptor (EGFR) promotes the development of NSCLC. Chemoresistance to tyrosine kinase inhibitors, which is elicited by EGF...
Autores principales: | Xu, Limei, Shi, Feifei, Wu, Yingdi, Yao, Shun, Wang, Yingying, Jiang, Xukai, Su, Ling, Liu, Xiangguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120120/ https://www.ncbi.nlm.nih.gov/pubmed/37085908 http://dx.doi.org/10.1186/s12964-023-01083-7 |
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