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Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants

BACKGROUND: Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interaction frequently accompanied by mental conditions, including depression and anxiety. Despite showing substantial heritability and being partly determined by a genetic component, the genetic underpinnings explaining t...

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Detalles Bibliográficos
Autores principales: Alemany, Silvia, Soler-Artigas, María, Cabana-Domínguez, Judit, Fakhreddine, Dana, Llonga, Natalia, Vilar-Ribó, Laura, Rodríguez-Urrutia, Amanda, Palacio, Judit, González-Castro, Ana María, Lobo, Beatriz, Alonso-Cotoner, Carmen, Simrén, Magnus, Santos, Javier, Ramos-Quiroga, Josep Antoni, Ribasés, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120121/
https://www.ncbi.nlm.nih.gov/pubmed/37085903
http://dx.doi.org/10.1186/s12967-023-04107-5