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pycoMeth: a toolbox for differential methylation testing from Nanopore methylation calls

We present pycoMeth, a toolbox to store, manage and analyze DNA methylation calls from long-read sequencing data obtained using the Oxford Nanopore Technologies sequencing platform. Building on a novel, rapid-access, read-level and reference-anchored methylation storage format MetH5, we propose effi...

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Detalles Bibliográficos
Autores principales: Snajder, Rene, Leger, Adrien, Stegle, Oliver, Bonder, Marc Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120131/
https://www.ncbi.nlm.nih.gov/pubmed/37081487
http://dx.doi.org/10.1186/s13059-023-02917-w