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pycoMeth: a toolbox for differential methylation testing from Nanopore methylation calls
We present pycoMeth, a toolbox to store, manage and analyze DNA methylation calls from long-read sequencing data obtained using the Oxford Nanopore Technologies sequencing platform. Building on a novel, rapid-access, read-level and reference-anchored methylation storage format MetH5, we propose effi...
Autores principales: | Snajder, Rene, Leger, Adrien, Stegle, Oliver, Bonder, Marc Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120131/ https://www.ncbi.nlm.nih.gov/pubmed/37081487 http://dx.doi.org/10.1186/s13059-023-02917-w |
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