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Tumor-infiltrating CD36(+)CD8(+)T cells determine exhausted tumor microenvironment and correlate with inferior response to chemotherapy in non-small cell lung cancer

BACKGROUND: The scavenger receptor CD36 was reported to be highly expressed on tumor-infiltrating CD8(+) T cells, but the clinical role remains obscure. This study aims to explore the infiltration and clinical value of CD36(+)CD8(+) T cells in NSCLC. METHODS: Immunohistochemistry and immunofluoresce...

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Detalles Bibliográficos
Autores principales: Ao, Yong-Qiang, Gao, Jian, Zhang, Ling-Xian, Deng, Jie, Wang, Shuai, Lin, Miao, Wang, Hai-Kun, Ding, Jian-Yong, Jiang, Jia-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120154/
https://www.ncbi.nlm.nih.gov/pubmed/37085798
http://dx.doi.org/10.1186/s12885-023-10836-z