Blockade of CCR4 breaks immune tolerance in chronic hepatitis B patients by modulating regulatory pathways

BACKGROUND: Immunotargets including checkpoint inhibitors and toll-like receptor 8 agonists have recently gained attention for the recovery of hepatitis B virus (HBV)-specific T cell exhaustion in chronic hepatitis B(CHB). Chemokine receptors have a similar significant role during viral infections;...

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Detalles Bibliográficos
Autores principales: Khanam, Arshi, Ghosh, Alip, Chua, Joel V., Kottilil, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120209/
https://www.ncbi.nlm.nih.gov/pubmed/37081509
http://dx.doi.org/10.1186/s12967-023-04104-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120209/
https://www.ncbi.nlm.nih.gov/pubmed/37081509
http://dx.doi.org/10.1186/s12967-023-04104-8

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