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Dose–response prediction for in-vitro drug combination datasets: a probabilistic approach
In this paper we propose PIICM, a probabilistic framework for dose–response prediction in high-throughput drug combination datasets. PIICM utilizes a permutation invariant version of the intrinsic co-regionalization model for multi-output Gaussian process regression, to predict dose–response surface...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120211/ https://www.ncbi.nlm.nih.gov/pubmed/37085771 http://dx.doi.org/10.1186/s12859-023-05256-6 |