Activation of CB1R alleviates central sensitization by regulating HCN2-pNR2B signaling in a chronic migraine rat model

BACKGROUND: Central sensitization has been widely accepted as an underlying pathophysiological mechanism of chronic migraine (CM), activation of cannabinoid type-1 receptor (CB1R) exerts antinociceptive effects by relieving central sensitization in many pain models. However, the role of CB1R in the...

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Detalles Bibliográficos
Autores principales: Zeng, Xiaoxu, Mai, Jia, Xie, Hongjian, Yang, Ling, Liu, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120244/
https://www.ncbi.nlm.nih.gov/pubmed/37085778
http://dx.doi.org/10.1186/s10194-023-01580-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120244/
https://www.ncbi.nlm.nih.gov/pubmed/37085778
http://dx.doi.org/10.1186/s10194-023-01580-7

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