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Free zinc determines the formability of the vesicular dense core in diabetic beta cells

During the progression of type 2 diabetes, total body zinc deficiency disrupts the formability of the electron-dense core in beta-cell vesicles, but the mechanism is unclear. Using fluorescence imaging, transmission electron microscopy and pharmacokinetics assays, we established a strong link betwee...

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Detalles Bibliográficos
Autores principales: Xian, Yi, Zhou, Mengxuan, Hu, Yuanzhao, Liu, Jing, Zhu, Wenzhen, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120278/
https://www.ncbi.nlm.nih.gov/pubmed/37193129
http://dx.doi.org/10.1016/j.cellin.2022.100020