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Free zinc determines the formability of the vesicular dense core in diabetic beta cells
During the progression of type 2 diabetes, total body zinc deficiency disrupts the formability of the electron-dense core in beta-cell vesicles, but the mechanism is unclear. Using fluorescence imaging, transmission electron microscopy and pharmacokinetics assays, we established a strong link betwee...
Autores principales: | Xian, Yi, Zhou, Mengxuan, Hu, Yuanzhao, Liu, Jing, Zhu, Wenzhen, Wang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120278/ https://www.ncbi.nlm.nih.gov/pubmed/37193129 http://dx.doi.org/10.1016/j.cellin.2022.100020 |
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