Discovery of oseltamivir-based novel PROTACs as degraders targeting neuraminidase to combat H1N1 influenza virus

Annual and sporadic influenza outbreaks pose a great threat to human health and the economy worldwide. Moreover, the frequent mutation of influenza viruses caused by antigen drift complicates the application of antiviral therapeutics. As such, there is an urgent need for novel antiviral agents to ta...

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Detalles Bibliográficos
Autores principales: Xu, Zhichao, Liu, Xinjin, Ma, Xiaoyu, Zou, Wenting, Chen, Qi, Chen, Feifei, Deng, Xiaofei, Liang, Jinsen, Dong, Chune, Lan, Ke, Wu, Shuwen, Zhou, Hai-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120310/
https://www.ncbi.nlm.nih.gov/pubmed/37193052
http://dx.doi.org/10.1016/j.cellin.2022.100030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120310/
https://www.ncbi.nlm.nih.gov/pubmed/37193052
http://dx.doi.org/10.1016/j.cellin.2022.100030

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