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Identification of a novel binding inhibitor that blocks the interaction between hSCARB2 and VP1 of enterovirus 71

Enterovirus 71 (EV-A71) infection causes severe hand-foot-and-mouth disease that leads to cardiopulmonary complications and death in young children under 5 years of age. Although there are available vaccines for EV-A71 C(4), however, there are no efficient drugs for severe cases. Thus, there is an u...

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Detalles Bibliográficos
Autores principales: Tang, Qi, Xu, Zhichao, Zhang, Fan, Cai, Yang, Chen, Yinuo, Lu, Baojing, Zhou, Hai-bing, Lan, Ke, Wu, Shuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120312/
https://www.ncbi.nlm.nih.gov/pubmed/37193133
http://dx.doi.org/10.1016/j.cellin.2022.100016