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CTLA4 prohibits T cells from cross-dressing
In this issue of JEM, Xiaozheng Xu et al. (2023. J. Exp. Med. https://doi.org/10.1084/jem.20221391) report that the inhibitory protein CTLA4 internalizes in cis the B7 stimulatory molecules previously “gnawed” by T cells from antigen-presenting cells (APCs) and in doing so prevents stimulatory T–T i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120349/ https://www.ncbi.nlm.nih.gov/pubmed/37071124 http://dx.doi.org/10.1084/jem.20230419 |