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Myeloid Src-family kinases are critical for neutrophil-mediated autoinflammation in gout and motheaten models

Autoinflammatory diseases include a number of monogenic systemic inflammatory diseases, as well as acquired autoinflammatory diseases such as gout. Here, we show that the myeloid Src-family kinases Hck, Fgr, and Lyn are critical for experimental models of gout, as well as for genetically determined...

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Detalles Bibliográficos
Autores principales: Futosi, Krisztina, Németh, Tamás, Horváth, Ádám I., Abram, Clare L., Tusnády, Simon, Lowell, Clifford A., Helyes, Zsuzsanna, Mócsai, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120404/
https://www.ncbi.nlm.nih.gov/pubmed/37074415
http://dx.doi.org/10.1084/jem.20221010