Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway

The Hippo pathway is a conserved and critical regulator of tissue growth. The FERM protein Expanded is a key signaling hub that promotes activation of the Hippo pathway, thereby inhibiting the transcriptional co-activator Yorkie. Previous work identified the polarity determinant Crumbs as a primary...

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Detalles Bibliográficos
Autores principales: Fulford, Alexander D., Enderle, Leonie, Rusch, Jannette, Hodzic, Didier, Holder, Maxine V., Earl, Alex, Oh, Robin Hyunseo, Tapon, Nicolas, McNeill, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120405/
https://www.ncbi.nlm.nih.gov/pubmed/37071483
http://dx.doi.org/10.1083/jcb.202204059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120405/
https://www.ncbi.nlm.nih.gov/pubmed/37071483
http://dx.doi.org/10.1083/jcb.202204059

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