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Styrylquinazoline derivatives as ABL inhibitors selective for different DFG orientations

Among tyrosine kinase inhibitors, quinazoline-based compounds represent a large and well-known group of multi-target agents. Our previous studies have shown interesting kinases inhibition activity for a series of 4-aminostyrylquinazolines based on the CP-31398 scaffold. Here, we synthesised a new se...

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Detalles Bibliográficos
Autores principales: Malarz, Katarzyna, Mularski, Jacek, Pacholczyk, Marcin, Musiol, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120462/
https://www.ncbi.nlm.nih.gov/pubmed/37070569
http://dx.doi.org/10.1080/14756366.2023.2201410