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Transcription tuned by S-nitrosylation underlies a mechanism for Staphylococcus aureus to circumvent vancomycin killing

Treatment of Staphylococcus aureus infections is a constant challenge due to emerging resistance to vancomycin, a last-resort drug. S-nitrosylation, the covalent attachment of a nitric oxide (NO) group to a cysteine thiol, mediates redox-based signaling for eukaryotic cellular functions. However, it...

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Detalles Bibliográficos
Autores principales: Shu, Xueqin, Shi, Yingying, Huang, Yi, Yu, Dan, Sun, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120478/
https://www.ncbi.nlm.nih.gov/pubmed/37085493
http://dx.doi.org/10.1038/s41467-023-37949-0