Immunogenicity and protective efficacy of SARS-CoV-2 mRNA vaccine encoding secreted non-stabilized spike in female mice

Establishment of an mRNA vaccine platform in low- and middle-income countries (LMICs) is important to enhance vaccine accessibility and ensure future pandemic preparedness. Here, we describe the preclinical studies of “ChulaCov19”, a SARS-CoV-2 mRNA encoding prefusion-unstabilized ectodomain spike p...

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Detalles Bibliográficos
Autores principales: Prompetchara, Eakachai, Ketloy, Chutitorn, Alameh, Mohamad-Gabriel, Tharakhet, Kittipan, Kaewpang, Papatsara, Yostrerat, Nongnaphat, Pitakpolrat, Patrawadee, Buranapraditkun, Supranee, Manopwisedjaroen, Suwimon, Thitithanyanont, Arunee, Jongkaewwattana, Anan, Hunsawong, Taweewan, Im-Erbsin, Rawiwan, Reed, Matthew, Wijagkanalan, Wassana, Patarakul, Kanitha, Techawiwattanaboon, Teerasit, Palaga, Tanapat, Lam, Kieu, Heyes, James, Weissman, Drew, Ruxrungtham, Kiat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120480/
https://www.ncbi.nlm.nih.gov/pubmed/37085495
http://dx.doi.org/10.1038/s41467-023-37795-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120480/
https://www.ncbi.nlm.nih.gov/pubmed/37085495
http://dx.doi.org/10.1038/s41467-023-37795-0

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