Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

Although the SARS-CoV-2 Omicron variant (BA.1) spread rapidly across the world and effectively evaded immune responses, its viral fitness in cell and animal models was reduced. The precise nature of this attenuation remains unknown as generating replication-competent viral genomes is challenging bec...

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Detalles Bibliográficos
Autores principales: Taha, Taha Y., Chen, Irene P., Hayashi, Jennifer M., Tabata, Takako, Walcott, Keith, Kimmerly, Gabriella R., Syed, Abdullah M., Ciling, Alison, Suryawanshi, Rahul K., Martin, Hannah S., Bach, Bryan H., Tsou, Chia-Lin, Montano, Mauricio, Khalid, Mir M., Sreekumar, Bharath K., Renuka Kumar, G., Wyman, Stacia, Doudna, Jennifer A., Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120482/
https://www.ncbi.nlm.nih.gov/pubmed/37085489
http://dx.doi.org/10.1038/s41467-023-37787-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120482/
https://www.ncbi.nlm.nih.gov/pubmed/37085489
http://dx.doi.org/10.1038/s41467-023-37787-0

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