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Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia

The currently recommended dose of dexamethasone for patients with severe or critical COVID-19 is 6 mg per day (mg/d) regardless of patient features and variation. However, patients with severe or critical COVID-19 are heterogenous in many ways (e.g., age, weight, comorbidities, disease severity, and...

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Detalles Bibliográficos
Autores principales: Blette, Bryan S., Granholm, Anders, Li, Fan, Shankar-Hari, Manu, Lange, Theis, Munch, Marie Warrer, Møller, Morten Hylander, Perner, Anders, Harhay, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120498/
https://www.ncbi.nlm.nih.gov/pubmed/37085591
http://dx.doi.org/10.1038/s41598-023-33425-3