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Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships

Vibrio cholerae causes life-threatening infections in low-income countries due to the rise of antibacterial resistance. Innovative pharmacological targets have been investigated and carbonic anhydrases (CAs, EC: 4.2.1.1) encoded by V. cholerae (VchCAs) emerged as a valuable option. Recently, we deve...

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Detalles Bibliográficos
Autores principales: Fantacuzzi, Marialuigia, D’Agostino, Ilaria, Carradori, Simone, Liguori, Francesco, Carta, Fabrizio, Agamennone, Mariangela, Angeli, Andrea, Sannio, Filomena, Docquier, Jean-Denis, Capasso, Clemente, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120512/
https://www.ncbi.nlm.nih.gov/pubmed/37073528
http://dx.doi.org/10.1080/14756366.2023.2201402