Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity

Design and synthesis of three novel series of aryl enaminones (3a–f and 5a–c) and pyrazole (4a-c) linked compounds with sulphonamides, sulfaguanidine, or carboxylic acid functionalities were reported as carbonic anhydrase inhibitors (CAIs) using the “tail approach” strategy in their design to achiev...

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Detalles Bibliográficos
Autores principales: Allam, Heba Abdelrasheed, Albakry, Mohamed E., Mahmoud, Walaa R., Bonardi, Alessandro, Moussa, Shaimaa A., Mohamady, Samy, Abdel-Aziz, Hatem A., Supuran, Claudiu T., Ibrahim, Hany S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120533/
https://www.ncbi.nlm.nih.gov/pubmed/37078174
http://dx.doi.org/10.1080/14756366.2023.2201403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120533/
https://www.ncbi.nlm.nih.gov/pubmed/37078174
http://dx.doi.org/10.1080/14756366.2023.2201403

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