CARD9 deficiency promotes pancreatic cancer growth by blocking dendritic cell maturation via SLC6A8-mediated creatine transport

Pancreatic cancer (PC) is featured with low survival rate and poor outcomes. Herein, we found that the expression of caspase-recruitment domain-containing protein 9 (CARD9), predominantly expressed in innate immune cells, was positively related to the prognosis of PC patients. CARD9-deficient PC mic...

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Detalles Bibliográficos
Autores principales: Tian, Cheng, Yuan, Huimin, Lu, Yi, He, Henghui, Li, Qing, Li, Senlin, Yang, Jian, Wang, Mengheng, Xu, Ruochen, Liu, Qian, Xiang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120541/
https://www.ncbi.nlm.nih.gov/pubmed/37089447
http://dx.doi.org/10.1080/2162402X.2023.2204015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120541/
https://www.ncbi.nlm.nih.gov/pubmed/37089447
http://dx.doi.org/10.1080/2162402X.2023.2204015

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