The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling

The scaffold protein IQGAP1 assembles multiprotein signaling complexes to influence biological functions. Cell surface receptors, particularly receptor tyrosine kinases and G-protein coupled receptors, are common IQGAP1 binding partners. Interactions with IQGAP1 modulate receptor expression, activat...

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Detalles Bibliográficos
Autores principales: Thines, Louise, Roushar, Francis J., Hedman, Andrew C., Sacks, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120595/
https://www.ncbi.nlm.nih.gov/pubmed/37071417
http://dx.doi.org/10.1083/jcb.202205062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120595/
https://www.ncbi.nlm.nih.gov/pubmed/37071417
http://dx.doi.org/10.1083/jcb.202205062

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