Cargando…

Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development

The transcription factors MECOM, PAX8, SOX17 and WT1 are candidate master regulators of high-grade serous ‘ovarian’ cancer (HGSC), yet their cooperative role in the hypothesized tissue of origin, the fallopian tube secretory epithelium (FTSEC) is unknown. We generated 26 epigenome (CUT&TAG, CUT&...

Descripción completa

Detalles Bibliográficos
Autores principales: Nameki, Robbin A., Chang, Heidi, Yu, Pak, Abbasi, Forough, Lin, Xianzhi, Reddy, Jessica, Haro, Marcela, Fonseca, Marcos AS, Freedman, Matthew L., Drapkin, Ronny, Corona, Rosario I., Lawrenson, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120620/
https://www.ncbi.nlm.nih.gov/pubmed/37090516
http://dx.doi.org/10.1101/2023.04.11.536378