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Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment

Tumor heterogeneity is a major driver of cancer progression. In epithelial-derived malignancies, carcinoma-associated fibroblasts (CAFs) contribute to tumor heterogeneity by depositing extracellular matrix (ECM) proteins that dynamically remodel the tumor microenvironment (TME). Ewing sarcomas (EwS)...

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Detalles Bibliográficos
Autores principales: Wrenn, Emma D., Apfelbaum, April A., Rudzinski, Erin R., Deng, Xuemei, Jiang, Wei, Sud, Sudha, Van Noord, Raelene A., Newman, Erika A., Garcia, Nicolas M., Hoglund, Virginia J., Bhise, Shruti S., Kanaan, Sami B., Waltner, Olivia G., Furlan, Scott N., Lawlor, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120623/
https://www.ncbi.nlm.nih.gov/pubmed/37090655
http://dx.doi.org/10.1101/2023.04.12.536619