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Optogenetic-Induced Muscle Loading Leads to Mechanical Adaptation of the Achilles Tendon Enthesis in Mice

The growth of the skeleton depends on the transmission of contractile muscle forces from tendon to bone across the extracellular matrix-rich enthesis. Loss of muscle loading leads to significant impairments in enthesis development. However, little is known about how the enthesis responds to increase...

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Detalles Bibliográficos
Autores principales: Ganji, Elahe, Lamia, Syeda N., Stepanovich, Matthew, Whyte, Noelle, Abraham, Adam C., Killian, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120626/
https://www.ncbi.nlm.nih.gov/pubmed/37090593
http://dx.doi.org/10.1101/2023.04.11.536376