The time integral of BMP signaling determines fate in a stem cell model for early human development

How paracrine signals are interpreted to yield multiple cell fate decisions in a dynamic context during human development in vivo and in vitro remains poorly understood. Here we report an automated tracking method to follow signaling histories linked to cell fate in large numbers of human pluripoten...

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Detalles Bibliográficos
Autores principales: Teague, Seth, Primavera, Gillian, Chen, Bohan, Freeburne, Emily, Khan, Hina, Jo, Kyoung, Johnson, Craig, Heemskerk, Idse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120633/
https://www.ncbi.nlm.nih.gov/pubmed/37090515
http://dx.doi.org/10.1101/2023.04.10.536068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120633/
https://www.ncbi.nlm.nih.gov/pubmed/37090515
http://dx.doi.org/10.1101/2023.04.10.536068

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