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The time integral of BMP signaling determines fate in a stem cell model for early human development
How paracrine signals are interpreted to yield multiple cell fate decisions in a dynamic context during human development in vivo and in vitro remains poorly understood. Here we report an automated tracking method to follow signaling histories linked to cell fate in large numbers of human pluripoten...
Autores principales: | Teague, Seth, Primavera, Gillian, Chen, Bohan, Freeburne, Emily, Khan, Hina, Jo, Kyoung, Johnson, Craig, Heemskerk, Idse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120633/ https://www.ncbi.nlm.nih.gov/pubmed/37090515 http://dx.doi.org/10.1101/2023.04.10.536068 |
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