Cancer heterogeneity is defined by normal cellular trade-offs

Gene expression predicts tumor characteristics such as resistance to anticancer therapy. However, generalizing these predictors to multiple cancer types and data sets to motivate new therapeutic strategies has proven difficult. Here, we present a nonnegative matrix factorization (NMF) approach that...

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Detalles Bibliográficos
Autores principales: Weistuch, Corey, Murgas, Kevin A., Zhu, Jiening, Norton, Larry, Dill, Ken A., Deasy, Joseph O., Tannenbaum, Allen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120658/
https://www.ncbi.nlm.nih.gov/pubmed/37090606
http://dx.doi.org/10.1101/2023.04.12.536595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120658/
https://www.ncbi.nlm.nih.gov/pubmed/37090606
http://dx.doi.org/10.1101/2023.04.12.536595

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