Characterization of Target Gene Regulation by the Two Epstein-Barr Virus Oncogene LMP1 Domains Essential for B-cell Transformation

The Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1) mimics CD40 signaling and is expressed by multiple malignancies. Two LMP1 C-terminal cytoplasmic tail regions, termed transformation essential sites (TES) 1 and 2, are critical for EBV transformation of B lymphocytes into immorta...

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Detalles Bibliográficos
Autores principales: Mitra, Bidisha, Beri, Nina Rose, Guo, Rui, Burton, Eric M., Murray-Nerger, Laura A., Gewurz, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120669/
https://www.ncbi.nlm.nih.gov/pubmed/37090591
http://dx.doi.org/10.1101/2023.04.10.536234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120669/
https://www.ncbi.nlm.nih.gov/pubmed/37090591
http://dx.doi.org/10.1101/2023.04.10.536234

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