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Computational Screen for Sex-Specific Drug Effects in a Cardiac Fibroblast Network Model

Heart disease is the leading cause of death in both men and women. Cardiac fibrosis is the uncontrolled accumulation of extracellular matrix proteins which can exacerbate the progression of heart failure, and there are currently no drugs approved specifically to target matrix accumulation in the hea...

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Detalles Bibliográficos
Autores principales: Watts, Kelsey M., Nichols, Wesley, Richardson, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120687/
https://www.ncbi.nlm.nih.gov/pubmed/37090681
http://dx.doi.org/10.1101/2023.04.11.536523