The contributions of DNA accessibility and transcription factor occupancy to enhancer activity during cellular differentiation

The upregulation of gene expression by enhancers depends upon the interplay between the binding of sequence-specific transcription factors (TFs) and DNA accessibility. DNA accessibility is thought to limit the ability of TFs to bind to their sites, while TFs can increase accessibility to recruit add...

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Detalles Bibliográficos
Autores principales: Long, Trevor, Bhattacharyya, Tapas, Repele, Andrea, Naylor, Madison, Nooti, Sunil, Krueger, Shawn, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120690/
https://www.ncbi.nlm.nih.gov/pubmed/37090616
http://dx.doi.org/10.1101/2023.02.22.529579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120690/
https://www.ncbi.nlm.nih.gov/pubmed/37090616
http://dx.doi.org/10.1101/2023.02.22.529579

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