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The contributions of DNA accessibility and transcription factor occupancy to enhancer activity during cellular differentiation
The upregulation of gene expression by enhancers depends upon the interplay between the binding of sequence-specific transcription factors (TFs) and DNA accessibility. DNA accessibility is thought to limit the ability of TFs to bind to their sites, while TFs can increase accessibility to recruit add...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120690/ https://www.ncbi.nlm.nih.gov/pubmed/37090616 http://dx.doi.org/10.1101/2023.02.22.529579 |