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The Impact of Stability Considerations on Genetic Fine-Mapping

Fine-mapping methods, which aim to identify genetic variants responsible for complex traits following genetic association studies, typically assume that sufficient adjustments for confounding within the association study cohort have been made, e.g., through regressing out the top principal component...

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Detalles Bibliográficos
Autores principales: Aw, Alan, Jin, Lionel Chentian, Ioannidis, Nilah, Song, Yun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120703/
https://www.ncbi.nlm.nih.gov/pubmed/37090514
http://dx.doi.org/10.1101/2023.04.11.536456