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Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction

Myocardial infarction is a leading cause of morbidity and mortality. While reperfusion is now standard therapy, pathological remodeling leading to heart failure remains a clinical problem. Cellular senescence has been shown to contribute to disease pathophysiology and treatment with the senolytic na...

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Detalles Bibliográficos
Autores principales: Redgrave, Rachael, Dookun, Emily, Booth, Laura, Folaranm, Omowumi, Tual-Chalot, Simon, Gill, Jason, Owens, Andrew, Spyridopoulos, Ioakim, Passos, Joao, Richardson, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120762/
https://www.ncbi.nlm.nih.gov/pubmed/37090497
http://dx.doi.org/10.21203/rs.3.rs-2776501/v1