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Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction
Myocardial infarction is a leading cause of morbidity and mortality. While reperfusion is now standard therapy, pathological remodeling leading to heart failure remains a clinical problem. Cellular senescence has been shown to contribute to disease pathophysiology and treatment with the senolytic na...
Autores principales: | Redgrave, Rachael, Dookun, Emily, Booth, Laura, Folaranm, Omowumi, Tual-Chalot, Simon, Gill, Jason, Owens, Andrew, Spyridopoulos, Ioakim, Passos, Joao, Richardson, Gavin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120762/ https://www.ncbi.nlm.nih.gov/pubmed/37090497 http://dx.doi.org/10.21203/rs.3.rs-2776501/v1 |
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