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Exit from Mitosis in Budding Yeast: Protein Phosphatase 1 is Required Downstream from Cdk1 Inactivation

We show that inactivation of the protein kinase Cdk1/Cyclin B (Cdc28/Clb 2 in the budding yeast Saccharomyces cerevisiae) is not only necessary for cells to leave mitosis, as is well known, but also sufficient to trigger mitotic exit. Cells carrying the mutation cdc28-as1, which makes Cdc28 (Cdk1) u...

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Detalles Bibliográficos
Autores principales: Keaton, Jason M., Workman, Benjamin G., Xie, Linfeng, Paulson, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120774/
https://www.ncbi.nlm.nih.gov/pubmed/37090579
http://dx.doi.org/10.21203/rs.3.rs-2787001/v1