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Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic

The accumulation of senescent cells has an important role in the phenotypical changes observed in ageing and in many age-related pathologies. Thus, the strategies designed to prevent these effects, collectively known as senotherapies, have a strong clinical potential. Senolytics are a type of senoth...

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Detalles Bibliográficos
Autores principales: Al-Mansour, Fares, Alraddadi, Abdullah, He, Buwei, Saleh, Anes, Poblocka, Marta, Alzahrani, Wael, Cowley, Shaun, Macip, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120895/
https://www.ncbi.nlm.nih.gov/pubmed/36988504
http://dx.doi.org/10.18632/aging.204616