A single-dose, randomized crossover study in healthy Chinese subjects to evaluate pharmacokinetics and bioequivalence of two capsules of calcium dobesilate 0.5 g under fasting and fed conditions

OBJECTIVES: To compare the rate and extent of absorption of a launched generic calcium dobesilate capsule versus the branded reference formulation under fasting and fed conditions in healthy Chinese subjects, and to assess their bioequivalence and tolerability. METHODS: This single-dose, open-label,...

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Detalles Bibliográficos
Autores principales: Liu, Yanmei, Cheng, Jie, Liang, Liyu, Qian, Weigang, Ou, Meixian, Zhang, Mengqi, Wang, Yijun, Wang, Yan, Peng, Ka, Jia, Jingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121042/
https://www.ncbi.nlm.nih.gov/pubmed/37083730
http://dx.doi.org/10.1371/journal.pone.0284576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121042/
https://www.ncbi.nlm.nih.gov/pubmed/37083730
http://dx.doi.org/10.1371/journal.pone.0284576

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